Sample Report

Personalized Immunogram & Transcriptomic Health Report

Immunogram History

Immune Age

Your current immune age is 38, compared to a biological age of 42. Your immune age went up by ~1 year in the last month.

Inflammation Score

Your inflammation score of 35 indicates moderately low systemic activity and inflammation. Your inflammation score went up by ~1 in the last month, possibly due to recent immune stress, infection, or metabolic imbalance.

Recovery Profile

Your recovery score of 80 is good, but your immune system may struggle with repeated stress. Improve sleep, stress, and nutrition. Your score dropped from 81 to 80 last month.

Expression Overview

123 genes upregulated
5600+ stable
87 genes downregulated

Highlighted Pathways

IL-6 Pathway

Activated +42%

Inflammatory

Elevated IL-6 activity suggests increased inflammation, which may contribute to fatigue or joint discomfort. Consider anti-inflammatory strategies like diet or exercise adjustments.

OxPhos Pathway

Suppressed −28%

Metabolic

Suppressed oxidative phosphorylation may indicate reduced cellular energy production. This could lead to fatigue or slower recovery. Focus on mitochondrial health through nutrition.

Type I Interferon

Activated

Immune

Activated interferon response indicates a strong antiviral defense, but if chronic, it may contribute to autoimmune risk. Monitor for signs of immune overstimulation.

NF-κB Signaling

Activated

Inflammatory

Activated NF-κB signaling points to heightened inflammation. This may increase the risk of chronic diseases. Stress management and anti-inflammatory foods may help.

TGF-β Regulation

Suppressed

Regulatory

Suppressed TGF-β regulation may impair immune balance, potentially increasing autoimmune risk. Support immune regulation through balanced nutrition and stress reduction.

Cytotoxicity Response

Activated

Immune

An activated cytotoxicity response indicates strong immune defense against infections or abnormal cells. However, if excessive, it may cause tissue damage. Monitor for balance.

Th2 Differentiation

Suppressed

Immune

Suppressed Th2 differentiation may weaken allergic or anti-parasitic responses. This could affect your response to certain infections. Consider immune-supportive supplements.

Celiac-like Signature

+12% expression risk

Autoimmune

Increased celiac-like signature raises the risk of gluten sensitivity or autoimmune reactions. Consider a gluten-free diet and consult a specialist for further evaluation.

Depression Signal

Moderate ↑

Neuroimmune

Elevated neuroimmune depression signals may link to mood changes or fatigue. Addressing inflammation and supporting mental health through therapy or lifestyle changes may help.

CD8 T cell signature

Elevated

Immune profile

Elevated CD8 T cell activity indicates a strong cytotoxic response, useful for fighting infections or cancer. Ensure balance to avoid excessive immune activation.